Many patients in the UK are now prescribed medical cannabis for IBS and other gastroenterological or gut issues, because of the potential relief the medication can offer from distressing symptoms. Medical cannabis is a rich source of cannabinoids, compounds that bind to receptors in the endocannabinoid system (ECS). The ECS affects multiple aspects of health, including mood, appetite, and the digestive system. Cannabinoids, most notably CBD and THC, may offer anti-inflammatory properties that may play a role in maintaining gut health.
The role of the endocannabinoid system in the gut is, in part, to promote intestinal homeostasis. Homeostasis is a state of balanced function in your body, and in the digestive system, this means that the immune system is regulated, the gut microbiome is healthy, and fluids can pass through the intestinal barrier as needed.
When someone suffers from a long-term digestive condition, many of these functions may be impacted, leading to pain, discomfort, and a reduced quality of life. Supportive medication for the endocannabinoid system could offer a therapeutic effect that helps soothe the gut.
Medical cannabis also has the potential to offer anti-inflammatory effects, helping patients deal with the pain and discomfort that accompany many chronic digestive complaints. The prescription of THC and CBD for IBS and other gut problems could also help alleviate the stress and anxiety that comes with these long-term diseases.
Which gastroenterological conditions can be treated with medical cannabis in the UK?
In the UK, there are many digestive conditions medical cannabis can be prescribed for, depending on the patient’s individual symptoms and needs. Inflammatory bowel disease (IBD), a long-term immune disorder that causes pain and diarrhoea, affects one in every 123 people in the UK. The two most common forms of IBD are Crohn’s disease, associated with pain and fatigue, and ulcerative colitis, where inflammation leads to ulcers in the colon and rectum.
Medical cannabis could offer relief for IBD symptoms via anti-inflammatory and anti-spasmodic properties, helping alleviate pain and cramping. A survey of Australian patients published in the journal Crohn’s & Colitis showed that 92.7% of 838 respondents endorsed medical cannabis as an effective way to manage symptoms, including pain, sleeplessness, anxiety, and cramps.
Some patients may be prescribed medical cannabis for IBS. IBS differs from IBD in that IBS isn’t an immune condition and inflammation isn’t the only symptom. People with IBS may experience pain, but also bloating, unpredictable bowel movements, and swings between constipation and diarrhoea. It’s possible to have both IBD and IBS.
Can medical cannabis for IBS help?
If you’re prescribed medical cannabis for IBS, it may be to help with the following symptoms:
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Medical cannabis for IBS – symptoms that may be relieved
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How symptom presents
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How medical cannabis for IBS may help
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Pain
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IBS causes stomach pain, bloating, and swelling that can be very uncomfortable. Constipation can lead to further pain due to straining.
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Many patients find that medical cannabis offers some relief for chronic pain, helping to improve their overall quality of life.
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Cramps
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Lower abdominal cramping is common with IBS, especially after eating.
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Evidence suggests that medical cannabis has anti-spasmodic properties which could help alleviate the impact of cramps.
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Sleep disorders
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Digestive discomfort and worry caused by a chronic condition may lead to insomnia or broken sleep.
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Some patients find medical cannabis helps improve their sleep, reducing fatigue and improving their mood.
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Anxiety
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Persistent feelings of stress, being on edge, intense worry, and nervousness, often caused by the unpredictability of the condition.
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Research from 2025 concluded that medical cannabis offers a therapeutic effect for both generalised and social anxiety disorders.
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Depression
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Low mood, feelings of helplessness, and an inability to perform daily tasks.
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Positively impacting the endocannabinoid system could help regulate the systems associated with improved mood.
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How effective is medical cannabis for digestive symptoms?
The effectiveness of medical cannabis for IBS, IBD, and other digestive symptoms varies from patient to patient. Some people may find that the medication helps alleviate the pain enough that they can return to activities they love, or perform daily tasks more easily. Others might find that their sleep improves, reducing fatigue levels and gradually improving their overall quality of life. The largest survey of active UK medical cannabis patients ever conducted showed that 97% of the 1,669 respondents reported quality of life improvements.
Patient stories offer anecdotal evidence of the potential therapeutic effects of medical cannabis for IBS. One patient said:
“I've lived with this problem: either intense diarrhoea or intense constipation. I've tried everything. I've exhausted other options. I've tried the dietitian. I've tried medicinal chemist-type products, and nothing worked. I'm just so pleased with the results that I'm happy to tell anybody. Let people know that maybe it won't work for everybody or every complaint, but for me it certainly worked.” Anthony, a Releaf patient.
How do you access medical cannabis for digestive conditions in the UK?
If you're one of the millions of people in the UK struggling with ongoing digestive conditions, you can use the medical cannabis eligibility checker on the Releaf website to find out if medical cannabis could be the next step for you. It takes about 30 seconds, and if you’re eligible for a consultation, you can book that right away.
Here’s how Releaf pricing works:
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Releaf Pay As You Go
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Releaf+.
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Initial consultation fee
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£99
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£99
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Prescription cost
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£19.99 plus £4.99 delivery
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Discounted rates
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Follow-up consultation fee
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£69.99
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Included
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Additional benefits
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Blogs, articles, and many other online resources. Learn the differences between indica vs sativa strains of plants or get information about medical cannabis travel certificates.
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Everything included on the Pay As You Go plan, plus extras like a rewards scheme and Releaf Protect, a service that offers free legal advice on all aspects of medical cannabis.
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One of the top concerns people have about opting for medical cannabis is remaining safe and legal. For your peace of mind, all Releaf patients are eligible for a UK medical cannabis card. Once you’ve paid for your first prescription, the card is completely free of charge. It’s delivered separately from your medication and usually takes 3-5 days to arrive. While a medical cannabis card can’t prevent the police from speaking to you, it does help you quickly identify yourself as a legal medical cannabis patient.
Releaf is the most trusted UK medical cannabis clinic, with a world-class clinical team of over 50 specialists, including medical professionals with extensive experience and understanding of a range of digestive conditions.
If you’re ready to join the Releaf community, check your eligibility online or contact our team.