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Menopause medical cannabis treatment

When ovaries stop producing eggs and the menstrual cycle ends, the menopause begins, and the body has to get used to hormonal changes in oestrogen and progesterone levels. The menopause can cause a myriad of symptoms that are typically treated with hormone replacement therapies, but, recently, increasing numbers of women are turning to cannabis-based menopause treatments for relief.

74%

of women taking cannabis in a study believe it helps manage menopause symptoms

Only 15%

of women in England choose to take HRT for menopause

90%

of women experience menopause symptoms

86%

of menopausal women have problems with sleep

Symptoms

Anxiety

Headaches

Hot flushes

Issues concentrating (brain fog)

Mood Swings

Muscle aches

Sleeping problems

Vaginal dryness

If you are displaying these symptoms, you may be going through the menopause. Please speak with your GP to find out more.

Treatment options:

The menopause is a natural biological event that is inevitable for anyone with a womb, and so there is no cure or prevention. There are a number of conventional medications that are typically prescribed to help manage the symptoms of menopause; however, like every form of treatment - they are not appropriate or successful for everyone.

Clonidine

Gabapentin

Hormone Replacement Therapy (HRT)

Oestrogen Treatments

Progesterone

Testosterone

Find out if you may be eligible for medical cannabis menopause treatments here

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Whether you’re new to cannabis-based medicines, switching from another medical cannabis clinic, or self-medicating, we’ll put you back in control of your health.

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A word from our specialist

"Medical cannabis can help alleviate some symptoms associated with menopause. Research has found that it can reduce Hot Flashes, improve sleep quality and duration, control mood swings and even reduce anxiety. Our patients with menopause have all reported a large improvement in their quality of life after just 1 month of treatment."

Alex Van Heerden Releaf Medical Cannabis Doctor

Dr Alex Van Heerden

Generalist

Find out if you may be eligible for medical cannabis menopause treatments here

Articles on Menopause

06. 08. 2025

What are the qualifying conditions for a UK medical cannabis prescription?

In this article we will look at the different medical conditions and routes of access UK patients can legally obtain a medicinal cannabis prescription through. Releaf recently conducted public surveys and published a report with the data titled Say No To Pain revealing 58.5% of the British population are likely to be unaware of the current medical cannabis laws.

Can medical cannabis treatments help symptoms of the menopause?

In 2023, a survey of 1485 women over the age of 35 (35% were postmenopausal and 33% perimenopausal), 34% reported they were currently taking cannabis – with 75% of those saying they were doing so for medical purposes, most commonly for sleep, anxiety and muscle/joint achiness. 74% of those currently taking cannabis believed the plant helped manage menopause symptoms. 

Beyond self-reported benefits, there are many studies supporting this experience, albeit not in studies specifically about menopause but in research exploring symptoms such as insomnia, anxiety, mood fluctuations, hot flushes, burning mouth syndrome and nervous system dysregulation. However, prominent groups such as The Menopause Society and The Society of Obstetricians and Gynaecologists of Canada (SOGC) have yet to officially recommend cannabis for treating menopause.

Concurrent with much global women’s health data, there remains a paucity in research into cannabis for menopause. 

Perimenopause, menopause and post-menopause: what the terms mean

Perimenopause

Perimenopause generally starts in a woman’s mid-40s as the ovaries begin to make less estrogen and progesterone in the run-up to menopause. During this time, periods can become irregular and heavy, then gradually lighten until they stop completely. Several symptoms commonly occur due to hormonal changes, often including sleep problems, mood changes, vaginal and bladder changes (such as dryness, discomfort or an urgent need to urinate) and hot flashes. This is the transition to menopause.

Menopause

Menopause begins 12 months after a woman’s final menstrual period, marking a new biological phase in life where natural pregnancy is no longer possible. Ovarian follicles deplete, and eggs are no longer released. For some women, the new normal of having very low estrogen and progesterone (which gradually declined during perimenopause) can bring about similar but sometimes stronger symptoms that occurred during perimenopause. These might include insomnia, brain fog, mood shifts, discomfort during sex, night sweats, weight gain and bone density loss.

Post-menopause

Post-menopause is considered to start 12 months after a woman’s periods stopped completely. This marks a new, permanent phase in life. At this time, menopause symptoms settle as the body regulates and adjusts to its new way of being. However, low estrogen can continue to increase the risk of osteoporosis and heart disease over time.

Which menopause symptoms might medical cannabis help with? 

Hot flushes and night sweats

Anecdotally, some women report that medical cannabis helps with hot flushes and night sweats, but clinical evidence is very limited. There is, however, a small-scale study looking at synthetic THC for the treatment of night sweats in cancer patients, in which all five patients found it to be effective. The study concluded that medical cannabis might be a promising therapy for the management of night sweats.

Sleep

Sleep issues and cannabinoids are well studied, and overall research suggests cannabis may help with insomnia and other sleep disturbances if used appropriately at the right dose. Studies also show that chronic use of high-dose cannabis can cause sleep issues and decrease REM sleep. 

THC and CBN are the two cannabinoids best known for treating sleep problems such as insomnia. CBD has also been found to be supportive, but studies on the isolated effects of CBD on sleep architecture are limited and mostly have mixed results. 

A 2020 a clinical review titled ‘Cannabinoid therapies in the management of sleep disorders: A systematic review of preclinical and clinical studies’reported that there is ‘promising preliminary evidence’ that provides ‘the rationale for future randomised controlled trials of cannabinoid therapies in individuals with sleep apnea, insomnia, post-traumatic stress disorder-related nightmares, restless legs syndrome, rapid eye movement sleep behaviour disorder, and narcolepsy’. However, further investigation is needed.

Anxiety and mood

As exacerbation or triggering of anxiety, depression and mental health conditions is widely discussed as one of the main risks of taking cannabis, yet some studies have also shown it can help with these issues, it may come as no surprise that results in this area are mixed. The most positive results for anxiety and mood tend to be self-reported by patients. 

Joint and muscle pain

People who take cannabis for menopause sometimes do so to address joint and muscle pain. Cannabinoids for chronic pain disorders such as fibromyalgia, cancer-related pain and neuropathic pain are a well-researched area, and THC in particular has been found to possess analgesic and muscle relaxing effects through modulation of the central nervous system.

One study explored the relationship between THC and CBD for pain, testing various inhaled doses and a placebo without THC or CBD. The combination of high THC and high CBD was found to significantly decrease pain, while other variants showed little difference from the placebo.

CBD or THC for menopause symptoms, what is the difference?

Both CBD and THC may be supportive for people experiencing symptoms of menopause, but in different ways.

CBD has no psychoactive effects and inhibits the enzyme that ordinarily degrades naturally produced endocannabinoids, resulting in higher levels in the bloodstream. CBD is best known for anti-inflammatory and antioxidant properties. 

THC is psychoactive and primarily acts on endocannabinoid receptors in the central nervous system (brain and spinal cord) and is often used to treat chronic pain and nausea.

Medical cannabis and HRT

Medical cannabis is not a hormone replacement therapy and does not replace one. It can be taken alongside HRT under clinical supervision, and some people find the combination to be very helpful, but anyone taking HRT should have their full medication list reviewed by the prescribing clinician. 

Where this sits alongside the other options a GP can offer

HRT is the most common first-line treatment for menopause symptoms. There are also some non-hormonal medications available such as fezolinetant (Veoza) and clonidine. In addition, some people find lifestyle and dietary changes can help, as well as cognitive behavioural therapy. Medical cannabis can be used alongside these treatments under clinical supervision.

Risks and side effects

Medical cannabis can interact with certain medications, so it’s important to follow the guidance provided by your Releaf clinician. Cannabis is also not suitable for everyone, particularly individuals with a history of bipolar disorder or schizophrenia. A full assessment will be conducted during the approval process to mitigate risks.

How to get assessed for medical cannabis for menopause in the UK

If you have already tried two or more frontline therapies to manage the symptoms of menopause, cannabis may be an option for you. Take a look at how Releaf works, then begin the approval process by filling in our medical cannabis eligibility checker online.

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